Using as input the raw UMIs, this function creates a domainogram for the supplied scales.
calculateDomainogram(umi4c, scales = 5:150, normalized = TRUE)
umi4c | |
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scales | Integer vector indicating the number of scales to use for the domainogram creation. Default: 5:150. |
normalized | Logical whether the the resulting domainograms should be normalized or not. Default: TRUE. |
A matrix where the first column represents the fragment end coordinates (start) and the rest represent the number of UMIs found when using a specific scale.